Diseases linked with low Skin Biodiversity

science reports...

The following is just a very small example of the latest skin microbiome research into the link between microbial diversity and common skin ailments and diseases.

Acne

The microbiota matters: In acne, it’s not us versus them

"Dysbiosis characterized by a lack of diversity is increasingly understood as a common theme in many skin disorders, and acne is no exception...."

By Kari Oakes
Dermatology News
2018

Eczema

There is a strong association between worsening disease severity and lower skin bacterial diversity.

"Atopic dermatitis (AD) flares are characterized by low bacterial diversity...."

By Giuseppe Baviera et al
BioMed Research International
2018

Dermatitis

Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis

"We report dramatic reductions in the skin microbial diversity during AD flares...."

By Heidi H. Kong et. al.
Genome Research
2012

Rosacea

Twin Study Shows Change in the Facial Microbiome May Impact Rosacea

"Their results conformed with earlier studies that showed there was less bacterial diversity when skin disease was present..."

National Rosacea Society
2018

Inflammation

The skin microbiome: impact of modern environments on skin ecology, barrier integrity, and systemic immune programming

"Studies show that dysbiosis and reduced diversity of skin microbes can influence the development of cutaneous inflammation and disease...."

By Susan L. Prescott et. al.
World Allergy Organization Journal
2017

Allergies

The microbiome in allergic disease: Current understanding and future opportunities

"Studies from Europe showing that living in a farming environment, which is linked to exposures to a diverse microbial community, is associated with a lower incidence of allergies."

By Yvonne J. Huang, et al.
The Journal of Allergy & Clinical Immunology
2017

Sunburn

The skin microbiome and immune system: Potential target for chemoprevention?

"A recent study demonstrated that the skin microbiome of cachectic cancer patients is less diverse than that of healthy participants"

By Mohammad Asif Sherwani et al.
Photodermatology, Photoimmunology & Photomedicine
2017

Athlete's Foot & Ringworm

Human Skin Fungal Diversity

"New treatment strategies are required to strategically target microbial dysbiosis and to combat the increasingly observed resistance against our current arsenal of antimicrobials."

By Keisha Findley et al.
Nature
2013

Wound Healing

The Wound Microbiome: Modern Approaches to Examining the Role of Microorganisms in Impaired Chronic Wound Healing

"Microorganisms are believed to play a significant role in impaired healing of chronic wounds and the development of infection-related complications.

By Ana M. Misic et al.
Advances in Wound Care
2014

Blepharitis & Conjunctivitis

Human Microbiota and Ophthalmic Disease

"Disruption of the normal ocular surface microbiota may play a significant role as a cofactor in the pathogenesis of ophthalmic diseases, such as contact lens-associated corneal infiltrative events, blepharitis, and post-operative infectious endophthalmitis."

By Louise J. Lu and Ji Liu
Yale Journal of Biology & Medicine
2016

Folliculitis & Pityriasis Versicolor
(fungal)

Healthy skin is actually cultivated by a well-balanced mix of bacteria and fungi (yeasts and molds).

"Malassezia yeasts are integral components of the skin microbiota, and therefore the therapeutic target should be controlling the Malassezia population rather than eradicating it..."

By Teun Boekhout
Fungal Biodiversity Center in Utrecht
2018

Diabetic Skin

A longitudinal study of the diabetic skin and wound microbiome.

"The diabetic skin microbiome was significantly less diverse than control skin...."

By Melissa Gardiner et al.
PeerJ
2017

Leishmaniasis

The microbiological signature of human cutaneous leishmaniasis lesions exhibits restricted bacterial diversity compared to healthy skin

"These findings demonstrate that traditional evaluation by culturing pathogenic bacteria is highly biased...."

By Salgado, et al.
Memórias do Instituto Oswaldo Cruz
2016

Skin Cancer

Bacteria on our bodies may be protecting us from skin cancer

"Your skin is crawling with bacteria – and some of them could be protecting you from cancer...."

By Jessica Hamzelou
New Scientist
2018

Dandruff

Dandruff Is Associated with Disequilibrium in the Proportion of the Major Bacterial and Fungal Populations Colonizing the Scalp

"Dandruff is linked to the balance between bacteria and fungi of the host scalp surface..."

By Cécile Clavaud, et al.
PLOS One
2016